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Beilstein J. Org. Chem. 2017, 13, 2690–2697, doi:10.3762/bjoc.13.267
Graphical Abstract
Figure 1: (a) UV–vis absorption and (b) fluorescence spectra of 1–4 in THF.
Figure 2: Fluorescence spectra of 1 and 3 in H2O:DMSO (9:1).
Scheme 1: Use of 1 as fluorogenic probe for DPP-4 activity.
Scheme 2: Synthesis of fluorogenic probe H-Gly-Pro-1.
Figure 3: Fluorescence spectra of 1 and H-Gly-Pro-1. Measurement conditions: 1.0 × 10−5 M in H2O:DMSO (9:1), ...
Figure 4: Fluorescence intensity changes of H-Gly-Pro-1 on addition of DPP-4.